By Siddhartha Mukherjee
From the Pulitzer Prize-winning, bestselling writer of The Emperor of All Maladies—a very good historical past of the gene and a reaction to the defining query of the longer term: What turns into of being human after we learn how to “read” and “write” our personal genetic information?
The outstanding Siddhartha Mukherjee has a written a biography of the gene as deft, significant, and illuminating as his terribly winning biography of melanoma. Weaving technological know-how, social historical past, and private narrative to inform us the tale of 1 of crucial conceptual breakthroughs of contemporary occasions, Mukherjee animates the search to appreciate human heredity and its marvelous effect on our lives, personalities, identities, fates, and choices.
Throughout the narrative, the tale of Mukherjee’s personal family—with its tragic and bewildering background of psychological illness—cuts like a vibrant, pink line, reminding us of the numerous questions that dangle over our skill to translate the technology of genetics from the laboratory to the genuine international. In terrific prose and with an intuition for the dramatic scene, he describes the centuries of study and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all through the progressive twenty-first century innovators who mapped the human genome.
As The New Yorker said of The Emperor of All Maladies, “It’s challenging to consider many books for a normal viewers that experience rendered any quarter of contemporary technological know-how and expertise with such intelligence, accessibility, and compassion…An impressive achievement.” Riveting, revelatory, and magisterial historical past of a systematic suggestion coming to lifestyles, and an important coaching for the ethical complexity brought via our skill to create or “write” the human genome, The Gene is a must-read for everybody interested by the definition and way forward for humanity. this can be the main the most important technology of our time, in detail defined by means of a grasp.
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Extra info for The Gene: An Intimate History
Engaging in ethical analysis involves (1) clarifying reasoning (implicit and explicit) used to justify a position, (2) identifying logical inconsistencies, and (3) determining the strength of arguments and their underlying rationale, for the purpose of determining the right or fair thing to do, understanding that the right—that is, the morally superior—thing to do is not necessarily the equally fair thing to do. How Do You Know an Ethical Issue When You See One? In reality, most of us get by fairly well in life without having to resort to philosophical analysis for help.
Physicians have a duty to protect a patient’s confidentiality. This duty is reinforced by the Health Insurance Portability and Accountability Act of 1996 (HIPAA),21 which established standards for the privacy and security of health information. However, such a duty is not absolute. 22 Whether genetic risks warrant similar exceptions, and if so, when, remains an important clinical concern. Several advisory committees have recommended that physicians be permitted to breach confidentiality to warn third parties only as a last resort to avoid serious harm.
In both examples, the general principle we uphold, that innocent lives must always be saved, enjoins incompatible actions. ). 32 • Just Genes When we engage in ad hoc justifications for our opinions about what’s right or wrong, we generally raise a host of normative issues, explicitly or implicitly, that typically creates more confusion than clarity. Identifying and analyzing claims, and their normative underpinnings, enable us to clarify our thoughts to make explicit rules and standards that are implicit in our judgments.
The Gene: An Intimate History by Siddhartha Mukherjee