By P. Portegies (auth.), Dr. Juan Artigas, Professor Dr. Gernot Grosse, Professor Dr. Fred Niedobitek (eds.)
Compact and obviously prepared, this ebook info current wisdom of AIDS study within the fields of neurology and ophthalmology.
The event won through medical specialists via operating with lots of sufferers is gifted including the distinct morphologic result of neuropathology. to explain a number of the illness complexes, morphology takes into consideration all equipment of consequence illustration, together with immunohistochemistry and electron microscopy.
The 4 disciplines pointed out within the subtitle describe all facets of the CNS with reference to AIDS, together with clinically major opthalmologic results.
Richly illustrated scientific and morphological descriptions enables you to comprehend the generally various CNS signs in addition to ophthalmic involvement.
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Additional resources for The Central Nervous System in AIDS: Neurology · Radiology · Pathology · Ophthalmology
After the onset of clinical symptoms the mean survival time is as short as 4 months. 1987; Hansman Whiteman et al. 1993). The foci of demyelination in PML appear hypodense (10--30 HU) on CT, without mass effect or contrast enhancement (Carrol et al. 1977). They are located in the white matter, involve the U fibers, and are not confined to the typical territories of vascular supply (Fig. 17). In the initial stage the lesions can be missed by CT. Gray et al. (1992) observed a patient with multiple, disseminated small PML foci limited to U fibers, whose CT was normal.
Atypical findings are the abscence of edema, mass effect, and even contrast enhancement (Bishburg et al. 1989; Ramsey and Geremia 1988). In patients with mUltiple lesions several patterns may coexist (Post et al. 1983). The enhancing properties of the lesions are, on the one hand, to some extent dependent on the immunological reactivity of the host. A strong immune reaction leads to a severe disturbance of the bloodbrain barrier and to massive contrast enhancement (Gaston et al. 1985). On the other hand, contrast-enhancement indicates the acuteness of a lesion during the course of the disease.
In a similar case report by Jankovic (1986), where no causative agent was isolated, MRI showed two lesions in the frontal regions of both hemispheres. The advantages of contrast-enhanced MRI were emphasized by the authors. 26 give examples of tuberculoma, brain abscess, and focal metastatic encephalitis. c Mycotic Infections of the eNS Cryptococcosis Meningoencephalitis caused by Cryptococcus neoformans is the most important generalized mycosis in AIDS. 26. MRI appearance of multiple brain abscesses ofthromboembolic origin.
The Central Nervous System in AIDS: Neurology · Radiology · Pathology · Ophthalmology by P. Portegies (auth.), Dr. Juan Artigas, Professor Dr. Gernot Grosse, Professor Dr. Fred Niedobitek (eds.)