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By Y C Janardhan Reddy, Shoba Srinath

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Extra info for Obsessive Compulsive Disorder. Current Understanding and Future Directions

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Cavedini et al (33), in their review, a temporary relief of anxiety (reward) but never feel 'full'. In relation to this, summarized the gambling task. This task requires 100 card selections from search for an immediate reward (relief of anxiety from compulsions), lack of four decks of cards identical in appearance; subjects are asked to maximize behavioral flexibility (continuous repetition of the same behavior), and their profit starting from a $2000 loan of play money. To attain this goal they blindness to negative future consequences the 'myopia for the future' must find the most advantageous decks and persistently pick up cards from (resulting in compromised life-quality) have all been described as characteristic those decks.

Marazziti et al (118) have shown dopamine and serotonin abnormalities Streptococcus (PANDAS) was coined. Patients with OCD precipitated by in patients with OCD. The behavior of rats treated chronically with the streptococci may initially have increased basal ganglia volume, perhaps with dopamine agonist, quinpirole, meets the ethological criteria of compulsive subsequent loss of volume. Also, such patients may respond to specific checking in OCD (119). Trials of combined SSRI and typical and atypical (see immunologic interventions, such as plasmapharesis or intravenous for review, 120, 121) antipsychotic treatment suggest that dopamine receptor immunoglobulin therapy.

Moreover, the findings suggested that the compulsive behaviors represent a failure to inhibit responding rather than a failure to properly complete a In a study examining the neural correlates of various symptom dimensions response. These findings are supported by a recent fMRI study in which OCD in OCD (46), patients demonstrated significantly greater activation than patients showed under-activation of fronto-striatal-thalamic-cortical circuitry controls in bilateral ventromedial prefrontal regions and right caudate nucleus during response inhibition.

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Obsessive Compulsive Disorder. Current Understanding and Future Directions by Y C Janardhan Reddy, Shoba Srinath


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