By Stephan C. Mann, Stanley N. Caroff, Paul E. Keck Jr., Arthur Lazarus
Neuroleptic malignant syndrome (NMS) and different hyperthermic stipulations are infrequent issues of antipsychotic medications which can reason soreness, incapacity, or even loss of life. therefore, each psychiatrist, general practitioner, and psychological healthcare professional has to be in a position to spot symptoms of NMS and to manage remedy in time to avoid a deadly end result. Neuroleptic Malignant Syndrome and similar Conditions is a crucial software for clinicians, outlining a framework for knowing, diagnosing, treating, and fighting those little-understood and sometimes overlapping issues. This new moment version largely updates and revises the 1st version, integrating an explosion of latest findings that experience happened because the past version used to be released in 1989.
A new bankruptcy on serotonin syndrome is very very important, given the increase in use of serotonergic medicinal drugs comparable to Selective Serotonin Reuptake Inhibitors (SSRIs). it's the first complete overview of this to seem on the earth literature.
Other chapters specialise in comparable stipulations reminiscent of antipsychotic drugвЂ“related heatstroke, hyperthermia linked to different neuropsychiatric medications, and malignant catatonia. The heatstroke bankruptcy includes a distinctive attention of thermoregulatory mechanisms, the disruption of which can underlie the pathogenesis of these types of stipulations.
Written by means of 4 the world over popular experts on NMS, Neuroleptic Malignant Syndrome and similar Conditions will equip clinicians with a realistic method in line with the most up-tp-date technology. additionally, this balanced monograph will stimulate learn, with insurance of controversies and unanswered inquiries to offer path for destiny research.
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Extra info for Neuroleptic Malignant Syndrome and Related Conditions
It may be that in some patients with NMS, severe respiratory abnormalities predominate; these patients may be predisposed to pulmonary problems on the basis of chronic obstructive pulmonary disease or a preexisting immune deficiency (Buffat et al. 1985). Persistent neuromuscular abnormalities have been reported in several patients with NMS. Residual muscle stiffness is not uncommon. S. Mueller 1985). S. Mueller et al. A. Anderson and Weinschenk 1987), resulting in weakness and sensory impairment.
M. Davis et al. 1991; Mann et al. 1990) and in the event of the development of a prolonged, residual catatonic or parkinsonian state following NMS (Caroff et al. 2000c). M. Davis et al. 7% for patients treated with Neuroleptic Malignant Syndrome ᪿ 35 medications and 21% for patients treated with supportive care alone. They found that patients who did not respond to ECT had continued to take antipsychotics. Mann et al. 2%) of 27 cases of NMS published in the literature. 38 days in NMS episodes, with most patients responding within 72 hours.
Hyperthermia associated with anticholinergic toxicity is also a consideration in the diagnosis of NMS but may be distinguished by the absence of rigidity, presence of atropinic signs, and response to physostigmine. A great deal of interest was generated by the overlapping clinical features of NMS and MH (Caroff et al. 1994a, 1994b, 2001c; Lazarus et al. 1989). MH is another drug-induced hypermetabolic syndrome that is associated with the administration of anesthetic gases and succinylcholine during anesthesia.
Neuroleptic Malignant Syndrome and Related Conditions by Stephan C. Mann, Stanley N. Caroff, Paul E. Keck Jr., Arthur Lazarus