Get Neonatal Neurology (Fourth Edition) PDF

By Gerald Fenichel MD

ISBN-10: 0443067244

ISBN-13: 9780443067242

Thoroughly up to date, completely referenced, and good illustrated, the fourth version of Gerald Fenichel's vintage assessment, Neonatal Neurology walks you thru the newest advances within the medical analysis and administration of neurological issues within the child.

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Extra resources for Neonatal Neurology (Fourth Edition)

Sample text

Perinatal hypoxic-ischemic thalamic injury: Clinical features and neuroimaging. Ann Neurol 1998;44:161–166. Scheuerle AE. Incontinentia pigmenti. (27 March 2003) In: GeneClinics: Medical Genetics Knowledge Base. [database online] University of Washington, Seattle. org Volpe JJ. Brain injury in the premature infant-neuropathology, clinical aspects, pathogenesis and prevention. Clin Perinatol 1997;24:567–587. Volpe JJ. Neurology of the Newborn, 4th edn. Philadelphia: WB Saunders, 2001;185–186. Wyatt JS.

Reduced fetal movement may occur when neuronal degeneration begins in utero. Affected newborns have generalized weakness involving proximal more than distal muscles, hypotonia, and areflexia. Newborns that are hypotonic in utero and weak at birth may have difficulty adapting to extrauterine life and experience postnatal asphyxia and encephalopathy. Most breathe adequately at first and appear alert despite the generalized weakness because facial expression is relatively well preserved and extraocular movement is normal.

Characteristic of the third phase is apparent improvement with normalization of tone. This may cause second thoughts about the accuracy of the diagnosis, but the improvement is short-lived. Evidence of neurological dysfunction begins to appear toward the end of the second month, and the symptoms become progressively worse throughout infancy. In premature newborns, the clinical features are subtle and may lack the phases of increased tone and opisthotonos. The typical clinical syndrome after the first year includes extrapyramidal dysfunction, usually athetosis, which occurs in virtually every case (see Ch.

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Neonatal Neurology (Fourth Edition) by Gerald Fenichel MD


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