Download e-book for kindle: Morphine - A Medical Dictionary, Bibliography, and Annotated by Icon Health Publications

By Icon Health Publications

ISBN-10: 0585498067

ISBN-13: 9780585498065

ISBN-10: 059784044X

ISBN-13: 9780597840449

This can be a 3-in-1 reference ebook. It offers a whole clinical dictionary protecting hundreds and hundreds of phrases and expressions with regards to morphine. It additionally provides broad lists of bibliographic citations. eventually, it offers info to clients on the way to replace their wisdom utilizing a variety of net assets. The publication is designed for physicians, scientific scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to get to grips with examine devoted to morphine. in the event that your time is effective, this booklet is for you. First, you won't waste time looking out the net whereas lacking loads of suitable details. moment, the ebook additionally saves you time indexing and defining entries. eventually, you won't waste time and cash printing hundreds and hundreds of websites.

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Additional info for Morphine - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

Example text

Therefore, our specific aims for the proposed funding period are to: 1) determine the second messenger(s) mediating the dynorphin and nociceptin effects on Im in CA1 hippocampal neurons. 2) Examine the effects of opioid on pharmacologically-isolated EPSCs and responses to NMDA, AMPA and kainate in CA1 of hippocampus. 3) Perform a battery of pharmacological tests to determine the site of action of chronic morphine treatment and possible changes in the postsynaptic NMDA receptor subunit composition in rat nucleus accumbens neurons.

In addition, our studies in slices of nucleus accumbens core confirmed the opiate reduction of synaptic transmission in the nucleus accumbens and found pronounced interaction of opiates with glutamate receptor agonists, and especially with those acting on non-NMDA and NMDA receptor-mediated neurotransmission, in neurons from rats treated chronically with morphine. Therefore, our specific aims for the proposed funding period are to: 1) determine the second messenger(s) mediating the dynorphin and nociceptin effects on Im in CA1 hippocampal neurons.

The specific aims are designed to test this hypothesis by: 1) determining the brain regions expressing CRE-responsive genes following morphine exposure; 2) monitoring the levels of the prohormone processing enzymes, PC1 and PC2, as well as bioactive peptide hormones in these regions; and 3) determining novel or uncharacterized genes/proteins regulated by various paradigms of morphine exposure in CREresponsive mouse brain regions. The focus of this proposal will be to use two new technologies, ProteinChip Array (SELDI-TOF Mass Spectrophotometry) and Gene Chip Array, to characterize and identify genes and proteins involved in opiate use.

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Morphine - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications


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