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Extra info for Mediaval : Patterns of the romanesque period
Participants, randomly selected, provided two timed 24-hr urine collections for assessment of Na, K, creatinine, urea, and completed four 24hr dietary recalls. BP was measured twice at each of four clinic visits. The study has been coordinated by two Coordinating Centers -- Northwestern University, Chicago and Imperial College of Medicine, London. Urinary determinations were made at a Central Laboratory in Leuven, Belgium. The 24-hr dietary recalls have been converted into nutrients with use in each country of an up-to-date, extensive, high quality, well maintained national data base, with international study-wide standardization and quality control.
Project 3, "Modulation of Signal Transduction Pathways by Tea Components" will focus on mechanisms key? to the inhibition of cell transformation and apoptosis in cell lines by caffeine and polyphenols as well as their derivatives, using cell and molecular biology approaches. Facilitated by the "Tea Chemistry and Analysis Core" and "Administrative Core, "the three Projects are highly interactive and integrated. Jointly, we intend to make major contributions to the use of tea for the I chemoprevention of cancer.
Enzyme activities will be determined by assaying appropriate blood and urine specimens for probe drugs and metabolites. Cognitive function will be tested and blood lymphocytes collected for measuring GST and NQO1 activities. Sixty subjects will then be randomly assigned to one of 4 double-blind treatment groups of 15 each: 1) ginseng extract (Ginsana), 2) ginkgo extract (EGb761), 3) both herbs, or 4) matching placebos. Tolerability of herbs will be determined. After 6 to 8 weeks of twice daily treatment with study agents, all effect parameters will be reevaluated: probe drug pharmacokinetics, cognitive function, and GST and NQO1 in blood lymphocytes.
Mediaval : Patterns of the romanesque period by L`Aventurine