By Madarasz, Louis
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Additional info for Lessons in Advanced Engraver's Script
1997 April; 77(4): 391-2. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=9155634 • Determination of plasma concentrations of losartan in patients by HPLC using solid phase extraction and UV detection. Author(s): Yeung PK, Jamieson A, Smith GJ, Fice D, Pollak PT. Source: International Journal of Pharmaceutics. 2000 August 25; 204(1-2): 17-22. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=11011981 • Differential effects of oral losartan and enalapril on local venous and systemic pressor responses to angiotensin I and II in healthy men.
By contrast, much less is known about AT1 mediated effects, however, it is generally accepted that there is a "yin yang" relationship. Functional data indicate that the AT2 receptor opposes the blood pressure elevation of the AT1 receptor and other cellular actions as well. Data is now accumulating that a major mechanism whereby the AT2 receptor regulates blood pressures is through its ability to facilitate Na excretion. The overall goal of the PPG is to elucidate cellular/molecular mechanisms important for the regulation of blood pressure through effects on ion transport.
Role of cytochrome P4502C and 3A subfamily members. Author(s): Stearns RA, Chakravarty PK, Chen R, Chiu SH. Source: Drug Metabolism and Disposition: the Biological Fate of Chemicals. 1995 February; 23(2): 207-15. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=7736913 • Blood pressure and renin angiotensin system responses to initiation of treatment with captopril or losartan in heart failure. Author(s): Squire IB, Robb S, Brennan G, O'Kane KP, Dargie HJ, Reid JL. Source: British Journal of Clinical Pharmacology.
Lessons in Advanced Engraver's Script by Madarasz, Louis