By Sandra Judd
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Extra info for Genetic Disorders Sourcebook, Fourth Edition (Health Reference Series)
It is important that any person who is considering genetic testing understand and weigh these factors before making a decision. What is genetic discrimination? Genetic discrimination occurs when people are treated differently by their employer or insurance company because they have a gene mutation that causes or increases the risk of an inherited disorder. People who undergo genetic testing may be at risk for genetic discrimination. The results of a genetic test are normally included in a person’s medical records.
Uninformative test results sometimes occur because everyone has common, natural variations in their DNA, called polymorphisms, that do not affect health. If a genetic test finds a change in DNA that has not been associated with a disorder in other people, it can be difficult to tell whether it is a natural polymorphism or a disease-causing mutation. An uninformative result cannot confirm or rule out a specific diagnosis, and it cannot indicate whether a person has an increased risk of developing a disorder.
Many cancer cells also have changes in their number of chromosomes. These changes are not inherited; they occur in somatic cells (cells other than eggs or sperm) during the formation or progression of a cancerous tumor. Can changes in the structure of chromosomes affect health and development? Changes that affect the structure of chromosomes can cause problems with growth, development, and function of the body’s systems. 15 Genetic Disorders Sourcebook, Fourth Edition These changes can affect many genes along the chromosome and disrupt the proteins made from those genes.
Genetic Disorders Sourcebook, Fourth Edition (Health Reference Series) by Sandra Judd