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Additional resources for Bipolar Disorder - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
This proposal provides for extensive development of his skills in molecular genetic methods. There will also be opportunities to learn statistical genetic methods. This will be accomplished through formal course work, extensive mentorship in a collaborative research environment, and implementation of a study that will be the first step toward a larger body of research aimed at investigating the genetics of bipolar disorder. Mentorship will be provided by Dr. J. , the director of the affective disorders genetics research group at Johns Hopkins, and by Dr.
Patients will provide blood samples for determination of platelet membrane phosphoinositides, which will be done with two-dimensional thin-layer chromotography followed by scanning laser densitometry. 5 T proton MRS brain scan, which will allow the quantitation of myoinositol in a voxel placed in the anterior cingulate. The career development plan will prepare the candidate for a full-time clinical research career devoted to the investigation of possible neurobiological mechanisms implicated in causation of bipolar disorder, and the mechanisms of action for the treatment of this condition.
Generate_Screen • Project Title: SPECT IMAGING OF DOPAMINE FUNCTION IN BIPOLAR DISORDER Principal Investigator & Institution: Anand, Amit;; Yale University 47 College Street, Suite 203 New Haven, Ct 065208047 Timing: Fiscal Year 2001 Summary: The study of amphetamne (AMPH) induced dopamine (DA) release in bipolar disorder will explore abnormalities in presynaptic dopamine release mechanisms as well as study post-synaptic DA receptors. The general aim of this study is to evaluate potential neurochemical correlates of AMPH challenge inpatients with bipolar disorder currently stable on the mood stabilizer--lithium.
Bipolar Disorder - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications, Health Publica Icon Health Publications